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The FDA recently declared NMN an investigational drug , not a dietary supplement

Notwithstanding significant progress in RNA therapies, their clinical efficacy is constrained by enduring obstacles, chiefly with delivery inefficiency, off-target effects, restricted tumor penetration, and hybridization-associated toxicities

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Chung CC, Kanetsky PA, Wang Z, Hildebrandt MA , Koster R, Skotheim RI, Kratz CP, Turnbull C, Cortessis VK, Bakken AC, Bishop DT, Cook MB, Erickson RL, Foss SD, Jacobs KB, Korde LA, Kraggerud SM, Lothe RA, Loud JT, Rahman N, Skinner EC, Thomas DC, Wu X, Yeager M, Schumacher FR, Greene MH, Schwartz SM, McGlynn KA, Chanock SJ, Nathanson KL